Players missing games due to positive Covid-19 tests could become even more prevalent as the season goes on, but we’re also starting to see an increase in “close contact” players being ruled out too.

From a pure healthcare standpoint it does make sense – especially when the NFL is preaching a mantra or safety first, but it will undoubtedly be infuriating for any players who test negative or feel okay.

San Francisco clearly have the worst injury issues going into Thursday night after Jimmy Garoppolo and George Kittle were ruled out, but the Packers have some issues of their own.

A.J Dillon was ruled out after a positive Covid test, and it appears that two of his teammates will also be side-lined after they were deemed to be close contacts:

The Packers have shared the touches around the backfield so far this year and Williams has played an important role, so they will really be pinning their hopes on Aaron Jones returning to full fitness but that does look doubtful.

Martin was starting to impose himself in the last couple of games and he looks like a promising defender with a bit of physicality about him, so he’ll still be a miss even if he’s a lower profile player.

The 49ers have so many injury issues with so many of their starters on injured reserve or clearly banged up so this should be an easier game for the Packers, but a lot could come down to Jones working his way to fitness.

A decimated backfield means it could be tough to establish the run, and San Fran still have enough of a pass rush to make life difficult for Rodgers and co if they can get going.

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